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ABSTRAKTNÍ

Nové syntetické opioidy (NSO) zahrnují různé analogy fentanylu a nově vznikající nefentanylové sloučeniny. Společně s nelegálně vyráběným fentanylem (MMF) způsobily tyto léky nedávný nárůst úmrtí na předávkování, zatímco úmrtí...

Abstract

Drug addiction refers to a broad phenotype, encompassing behavioral, cognitive, and biological (including genetic) substrates. Twin studies have estimated the heritability of drug addiction between 30% and 60%. Dopamine has a...

'Million Hearts' is an initiative launched by the U.S. Department of Health and Human Services that aims to prevent 1 million heart attacks and strokes by promoting evidence-based intervention through communities, health systems, non-profit...

Inclusion Health is a framework for action that helps find ways of improving the health and well-being for socially excluded groups. These populations, who have in common adverse life experiences and risk factors, such as poverty and...

Keeping Youth Drug Free is a new publication from the Substance Abuse and Mental Health Services Administration (SAMHSA). Aimed at parents, the guide offers advice for keeping children substance-free. It includes a review of the latest...

Seizing on the theory’s propaganda value, in 1997 the head of the US National Institute on Drug Abuse proclaimed, “Addiction Is a Brain Disease, and It Matters.” His contention has been hailed as a breakthrough or condemned as a...

Problem gambling in the UK is reported to affect around 590,000 people.

The condition can be treated via a range of approaches, including cognitive behavioural therapy and medication.

Published in the journal Translational Psychiatry, a...

Background: Long-term alcohol use is known to harm brain functioning in adolescence. In the central nervous system, the effects of alcohol are particularly mediated by alterations in GABAergic neurotransmission. Combining simultaneous...

Alcohol and nicotine are two of the most frequently abused drugs, with their comorbidity well described. Previous data show that chronic exposure to nicotine upregulates high-affinity nicotinic acetylcholine receptors (nAChRs) in several...

Nicotine is the addictive component of conventional cigarettes. E-cigarettes are available in a range of nicotine strengths. Those that contain nicotine were deemed recently to be subject to regulation by the US Food and Drug Administration...

12- to 17-year-olds in the US are now far less likely to misuse alcohol, nicotine and illegal drugs. The same age group is also less prone to delinquent behaviours, such as stealing and fighting than the generation before. This is according...

Lesbian, gay, and bisexual (LGB) individuals report higher levels of problematic alcohol and substance use than their heterosexual peers. This disparity is linked to the experience of LGB-specific stressors, termed minority stress...

V USA se méně než 10 % dospělých se souběžnými problémy s duševním zdravím a poruchami užívání návykových látek léčí s obojím. 50 % z nich se neléčí ani pro jedno.

To zdůrazňuje obrovský rozpor mezi prevalencí současně se vyskytujících...