Project Khanya: a randomized, hybrid effectiveness-implementation trial of a peer-delivered behavioral intervention for ART adherence and substance use in Cape Town, South Africa

Source:

Magidson, J.F., Joska, J.A., Myers, B. et al. Project Khanya: a randomized, hybrid effectiveness-implementation trial of a peer-delivered behavioral intervention for ART adherence and substance use in Cape Town, South Africa. Implement Sci Commun 1, 23 (2020). https://doi.org/10.1186/s43058-020-00004-w

Contributions to the literature

• Project Khanya will extend the existing literature by improving our understanding of the implementation of peer-delivered behavioral interventions for substance use and HIV medication adherence in a resource-limited setting with one of the greatest HIV burdens globally.

• Implementation science methods are needed to evaluate task sharing models in global mental health.

• Resource-limited settings with the greatest HIV burden face unique implementation barriers.

• A peer-delivered integrated behavioral intervention such as the one evaluated in Project Khanya may be a feasible, acceptable, efficient, and scalable approach to extending the reach of substance use care for people living with HIV globally.