Epidemiology and Etiology
Adolescent drug use before and during U.S. national COVID-19 social distancing policies
During the COVID-19 pandemic, countries around the world have introduced lockdown restrictions and social distancing measures to reduce the spread of the virus. Researchers are keen to understand how these policies and new measures have...

Lower regional grey matter in alcohol use disorders: evidence from a voxel-based meta-analysis
Background: Previous research using whole-brain neuroimaging techniques has revealed structural differences of grey matter (GM) in alcohol use disorder (AUD) patients. However, some of the findings diverge from other neuroimaging studies...
Association of genetic liability to smoking initiation with e-cigarette use in young adults: A cohort study
Background: Tobacco smoking and e-cigarette use are strongly associated, but it is currently unclear whether this association is causal, or due to shared factors that influence both behaviours such as a shared genetic liability. The aim of...
Disentangling substance use and related problems: urgency predicts substance-related problems beyond the degree of use
Background: Substance use disorders are reliably associated with high impulsivity and sensation seeking. Importantly, both precede problematic substance use, implicating them as risk factors. Individuals with substance use disorders show...
World Drug Report 2021
Consisting of five separate booklets, the World Drug Report 2021 provides an in-depth analysis of the global drug markets and paints a comprehensive picture of the measurable effects and potential impact of the COVID-19 crisis on the world drug problem.

A randomised, double-blind study investigating the relationship between early childhood trauma and the rewarding effects of morphine
Experiences of childhood trauma (abuse and neglect) are disproportionately higher in those with opioid use disorder (OUD). Childhood trauma may affect the reinforcing and rewarding properties of opioid drugs and responses to pain, potentially via developmental changes to the endogenous opioid system.

Global launch of the 2021 World Drug Report
The World Drug Report 2021 provides an analysis of the latest supply and demand of cannabis, opioids, cocaine and amphetamine-type stimulants.

Virtual Launch of the 2021 European Drug Report
How has the COVID-19 pandemic affected drug use and supply? What drugs are causing the most concern today? What are the latest trends in drug production and trafficking? Find out more in the recording of the online media event from 9 June...
New Benzodiazepines in Europe – A Review
Summary This report provides a technical review of the current body of knowledge regarding new benzodiazepines that are monitored by the EU Early Warning System. The aims of this report are to strengthen situational awareness of new...

European Drug Report 2021
The Trends and Developments report presents the EMCDDA’s latest analysis of the drug situation in Europe. Focusing on illicit drug use, related harms and drug supply, the report contains a comprehensive set of national data across these...
