Applying interventions designed to reduce and manage the symptoms of substance use disorders.
Treatment
HIV and people who use drugs: Factsheet
The 2021-2026 Global AIDS Strategy has bold and critical new targets on realizing human rights, reducing stigma, discrimination and violence and removing harmful punitive laws as a pathway to ending inequalities and ultimately ending AIDS...
HIV Prevention, Treatment, Care and Support for People Who Use Stimulant Drugs
Since the beginning of the HIV epidemic, the focus on HIV prevention, treatment and care among people who use drugs has concentrated on the needs of people who inject drugs, and mainly on those who inject opioids. However, data show that...
Correlates of treatment engagement and client outcomes: results of a randomised controlled trial of nabiximols for the treatment of cannabis use disorder
Introduction There is increasing interest and evidence for the use of cannabinoid medications in the treatment of cannabis use disorder, but little examination of the correlates of successful treatment. This paper is a secondary analysis of...
Brief counselling by a doctor can reduce drinking
A new systematic review and meta-analysis has found that alcohol-targeted brief interventions (short, structured, one-to-one conversations about drinking designed to motivate changes in risky behaviour) delivered in doctors’ offices and...
Placebo Response and Media Attention in Randomized Clinical Trials Assessing Cannabis-Based Therapies for Pain A Systematic Review and Meta-analysis
Abstract Importance Persistent pain is a common and disabling health problem that is often difficult to treat. There is an increasing interest in medicinal cannabis for treatment of persistent pain; however, the limited superiority of...
Transparency and governance in drug treatment systems: Online survey
This anonymous survey addresses the topic of transparency and governance in drug treatment systems. It is part of a broader project coordinated by researchers at the University of Vienna and Universitat de Barcelona. In the following...
Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure
Abstract Adolescent binge drinking is a major risk factor for psychiatric disorders later in life including alcohol use disorder. Adolescent alcohol exposure induces epigenetic reprogramming at the enhancer region of the activity-regulated...
Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD:THC ratios
Abstract As countries adopt more permissive cannabis policies, it is increasingly important to identify strategies that can reduce the harmful effects of cannabis use. This study aimed to determine if increasing the CBD content of cannabis...